plugging vicodin (apap rectal bioavailabilty)

hydrocondor So I have seen numerous threads on this subject, but no definite answer. does anyone know the rectal bioavailability of apap (paracetamol)? I am asking because it seems like it’d be nice and convenient to just be able to plug my vikes and avoid liver damage. Thanks, hydrocondor —— SDforever420 not really sure to…

tramadol with oxycodone

laCster i read somewhere that the oxy will force the tramadol out of the mu receptors and i wont get any effect from tramadol….i am hoping the tramadol will make the experience better… 60mg oxy and 100mg tramadol…hopefull it will turn out good! any responses on experiences or whatever would be helpful!! at the moment…

Help… Was on black tar now subs

iamstone First off, thank you for reading this. I do hope to get straightforward answers instead of judgements… I was on moderate black tar h on and off for about 4,5 months, been through some horrible withdrawals and also weak ones towards the end after I realized it’s because of my on and off crazy…

Tramadol chest pain

danceofdays I’m currently in the process of detoxing myself from opiates by doing an obnoxiously slow codeine taper in the hopes that a few months of steady dose reduction will get my receptors and the like back to normal. A few days ago I didn’t have time to do my normal extraction before work, so…

Average dose of meth for first time user?

a7xlover Hey guys im not asking for an exact number or anything, im just wondering how much is suitable for a first time user since i have practically no meth experience. how much did you take your first time? —— halfoz i have no idea how much i smoked the first time. at the point…

why are my vyvanse comedowns so harsh?

olab7 when i take vyvanse recreationally ill take around 90-100mg. ive taken it as early as 7am and i will still get insomnia and not be able sleep for about 30 hours after ive taken it. after around 12 hours of taking it i feel like crap. i feel very tired(yet cannot sleep), headache, which…

can you snort dex ir 5mg?

PeedOff i have like 30 of these SKF E19 shield shaped dextroamphetamine 5mg ir tablets are they snortable? theyre small pills but theres only 5mg per pill so thats alot of binder. —— TheTwighlight Yeah, you can snort them if you want, but if you want my personal advice, just take them. Will last longer…

Benzo and zolpidem cross tolerance and dosage

Snxjsjskakz I take benzos twice per week to sleep. When I take a benzo I take either 2mg Xanax, 2mg klonopin, or 40 mg of Valium. I have been taking the same dose at the same frequency for about a year now. I know that benzos and ambien are cross tolerant, so about what would…

A Comprehensive Self-Experiment With Nootropics

nootropia Background I’ve been interested in neuropharmacology for quite some time now, and after extensive research am ready to begin experimentation with various nootropics. While there is plenty of research on these substances individually (and in popular combinations), because of their synergistic effects and dramatic disparity in optimal effective dose from person to person, I…

pseudophedrine with kratom

jeffsleep was going to take a nightime cold tablet as a potentiator to the kratom i have taken tonight(tabs contain dxm and small doses of chlorpheniramine), right before i took them i saw that they contained pseudophedrine and realized i had never taken pseudophedrine with kratom, i then realized i had never taken it with…